Endocrine Abstracts

The two primary functions of the adult testis (sperm production and hormone production) need to be co-ordinated because sperm production is completely dependent on appropriate hormone (primarily testosterone) production. However, it is equally evident from animal studies that Leydig cell (LC) development and function are also affected by developmental and functional status of the seminiferous tubules. For example, development of the adult LC population is dependent on reduced ...

Smoking by women during pregnancy can result in a 30–48% reduction in sperm count and testis size in the exposed offspring in adulthood, probably because of a decrease in the number of Sertoli cells. Until recently Sertoli cell proliferation was thought to be androgen independent because fetal Sertoli cells do not express the androgen receptor, but new evidence suggests that androgens may play the lead role in regulating Sertoli cell proliferation in fetal (Tan et al.<...

Introduction: haemangiopericytoma is a rare soft tissue tumour originating from pericytes. These are often large and slow growing tumours and manifest rarely as hypoglycaemia. We report a case of haemangiopericytoma-induced hypoglycaemia.Case report: A 72-year-old lady presented with an episode of confusion. She had had similar episodes usually in the early morning hours. She was also known to have hypertension and a large bladder haemangio...